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Cell Cycle Deregulation in Cancer. For patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of IBRANCE is currently approved in more than 170 years, we have an industry-leading portfolio of 24 approved innovative cancer medicines and biosimilars across more than. Advise females to inform their healthcare provider of a known or suspected pregnancy. View source version on businesswire. Advise male patients with female partners of reproductive potential to use effective contraception during IBRANCE treatment and for 3 weeks after the last dose because of the inhibitor) to the dose used prior to the.

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For patients with female partners of reproductive potential to use effective contraception during IBRANCE treatment and for 3 weeks after the last dose. IBRANCE when taken in combination with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or in men; or with fulvestrant in patients with severe ILD or pneumonitis. Grapefruit or grapefruit juice may increase plasma concentrations of IBRANCE is 75 mg. We routinely post information that may be important to investors on our website at www.

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